In HF myocytes, however, KB β-OHB almost doubled the percentage of HF cells with Parkin-rich regions; however, this did not increase LC3-mediated autophagosome formation, suggesting that even though there was upregulation in Parkin, the impairment in mitophagic signaling persisted or was even exacerbated. This evidence concerns the gene MAP1LC3A and hydrops fetalis.