Also, some of the galectin family members (for example galectin-3) were found to be able to protect AML and colorectal cancer cells against apoptosis through mitochondrial stabilization in a B cell lymphoma protein (Bcl) 2-dependent manner (Lee et al., 2013; Ruvolo, 2016). The gene discussed is LGALS3; the disease is acute myeloid leukemia.