MAPK8 and asthma: JNKs have also been implicated in the pathogenesis of asthma (Liang et al., 2016), and several pro-inflammatory genes, including adhesion molecules (Korenaga et al., 1997), growth factors (Hata et al., 2000), and intercellular adhesion molecule 1 (Lee et al., 2015) are regulated by the JNK MAPK pathway.