NOTCH1 and amyotrophic lateral sclerosis: Our results show that expression of markers of proliferation (Ki67), differentiating cells (GFAPδ), and differentiation (PSA-NCAM) is significantly correlated with NICD expression and negatively correlated with Notch1, which suggests that decreased neurogenesis in ALS (Galán et al., 2017) may be associated with Notch signalling pathway inactivation.