In the majority of cases, BRVO occurs when a first- or second-order retinal vein focally occludes at an arteriovenous (AV) crossing5–9, and results in the development of macular edema (ME)4,10 and a retinal nonperfusion area (NPA)4,10–12 under upregulation of vascular endothelial growth factor (VEGF)13,14. Here, VEGFA is linked to macular retinal edema.