In mice models of tumor growth and orthotopic metastasis established by subcutaneous and injected into serous of cecum with CRC cells, we found that GSTP1 enhanced primary tumor growth (P < 0.01, Fig. 5a) and significantly increased the number of metastatic liver nodules in mice (P < 0.05, Fig. 5b). Here, GSTP1 is linked to neoplasm.