To evaluate the expression correlation of FBX8 and GSTP1 in CRC tissues, we detected the expressions of FBX8 and GSTP1 in 18 paired samples of fresh CRC tissues and fresh colon tissues of FBX8-WT and FBX8 KO mice treated with AOM-DSS. The gene discussed is FBXO8; the disease is colorectal carcinoma.