MEP1B and type 1 diabetes mellitus: The current study employed global metabolomics analysis to evaluate the metabolite profiles of urine and plasma samples from WT mice (which express normal levels of both meprin A and meprin B) and meprin β KO mice which are deficient in meprin B (β-β) and heterodimeric meprin A (α-β) following induction of type 1 diabetes.