Increased Nrf2 levels have been shown in many clinical cancer studies including melanoma, lung, ovarian and endometrial carcinomas, pancreatic cancer, renal cancer, breast, colorectal cancer and hepatocellular carcinoma, and etc. Table 1 [59,60,61,62,63,64,65,66,67,68,69,70,71,72,73,74,75,76,77,78]. Here, NFE2L2 is linked to colorectal cancer.