ALB and chronic kidney disease: Several factors have been reported to alter %PB of PBUTs during CKD: i.e., lower albumin levels due to increased protein catabolism rate and/or albumin losses, and a lower binding affinity to albumin due to post-translational modifications (e.g., oxidation, carbamylation, nitrosylation, glycation, and acetylation) [9,10,37,38,39].