IFNG and osteogenesis imperfecta: Adult-onset immunodeficiency due to anti-interferon-gamma autoantibodies (anti-IFN-γ auto-Abs) is a distinct clinical syndrome of disseminated nontuberculous mycobacteria (NTM) or other opportunistic (OI) infections in previously healthy adult patients in association with anti-IFN- γ auto-Abs [1].