The prevalence of hyponatremia in the emergency department (ED) is reported to range from 2.3–44%, while prevalence of hypernatremia is 1.1–4.4%, hypokalemia 10.2–39%, hyperkalemia 0.8–13%, and albumin-corrected hypercalcemia 0.7–7.5% [1, 2, 6, 10–13]. The gene discussed is ALB; the disease is Hyponatremia.