CD274 and breast cancer: As expected based on PD-L1 and PD-1 expression and immune infiltrate profile, BRCA1-, but not BRCA2-, deficient breast cancers were associated with higher T cell-inflamed signature in WSI (P = 1.9 x 10−7 and 0.072, respectively) and TCGA (P = 8.0 x 10−3 and 0.95, respectively) (Table 1).