Interestingly, transcription factor (such as Snail, Slug, ZEB1, SIP1 and Twist), as a key regulators of EMT, was found to be an intracellular element related to cellular proliferation, invasion and metastasis.21 Herein, we discovered the role of Slug in AKIP1‐mediated regulation of GC proliferation and metastasis. This evidence concerns the gene AKIP1 and gastric cancer.