Cohorts of Spata13 homozygous knockout animals and wildtype controls were behaviourally assessed using the light–dark box (anxiety and exploratory behaviour), marble burying (stereotypical compulsive behaviour), von Frey filament test (mechanical sensitivity), hot plate (thermal sensitivity), working memory (forced alternation y-maze) and fear conditioning (cued and contextual memory). The gene discussed is SPATA13; the disease is Anxiety.