In our previous studies, we have elucidated that CP could reduce the expression of HBxAg in transplant tumors, and we also verified that CP could inhibit HBV-DNA replication and reduce the expression of URG4, URG7, URG11, and URG9, preventing and delaying the development of HBV-related HCC in patients treated with CP for two years [16–18]. The gene discussed is VWCE; the disease is hepatocellular carcinoma.