Figure 4 clearly demonstrates that genes associated with B cells [BTK, CD19, IGH, IGK, IGL, MS4A1 (CD20)], T cells (CD3E, CD4, CD8a, CD8b, ICAM1, ITK, TRA TRB, TRD, TRG), neutrophils (CTSG, ELANE, MPO), neutrophil-recruiting (CXCL1, CXCL2, CXCL5, IL8), and psoriasis-associated inflammatory cytokines (IL1B, IL17A, IL23A, IL36A, IL36B, IL36G) cluster well together in distinct groups, which supports this method as a means to visualize the entire psoriasis transcriptome. The gene discussed is MS4A1; the disease is psoriasis.