Conversely, a wide range of neurodegenerative disorders, such as Alzheimer’s (Cho et al., 2009; Manczak et al., 2011; Manczak and Reddy, 2012), Huntington’s (Costa et al., 2010; Song et al., 2011; Shirendeb et al., 2012) and Parkinson’s diseases (Wang et al., 2011) are associated with increased Drp1 levels and mitochondrial fragmentation (Hu et al., 2017). This evidence concerns the gene DNM1L and Parkinson disease.