SCD and breast carcinoma: Notably, SCD1 is highly expressed in oncogene-transformed lung fibroblasts and cancer cells, and is involved in sustaining rapid cancer cell proliferation, evading cell apoptosis, facilitating cancer cell initiation and malignant transformation in various types of cancers including leukemia [9], breast cancer [10], renal cancer [11], lung cancer [12], hepatocarcinoma [13] etc. We previously identified overexpression of SCD1 in tumor tissues of NSCLC patients and aberrantly high levels of SCD1 are predicted as a poor clinical outcome in patients with lung cancer [14].