HNRNPL and B-cell chronic lymphocytic leukemia: To determine if HNRNPL interacts with BUB1 3′UTR in B-CLL cells as occur in T cells (Figure S4), we performed RNA immunoprecipitation (RIP) analysis in HG-3 cells, a CLL cell line in which we transfected the vectors carrying the BUB1 3′UTR with either 18CA or 19CA (the most representative alleles) downstream of the luciferase reporter gene.