Significant differences were observed between the normoalbuminuria and microalbuminuria groups with respect to age, proportion of female patients, patients with hypertension, use of angiotensin converting enzyme inhibitors (ACEi) or angiotensin-receptor blockers (ARBs), SBP, HbA1C, and TG (P < 0.05). The gene discussed is ACE; the disease is Hypertension.