MiR‐132 was upregulated in GBMs and was a potential indicator of poor prognosis.35, 36 MiR‐127 and miR‐433 are both derived from an overlapping gene locus and colocalized within a cancer‐associated genomic region.37 MiR‐127 was reported to promote GBM cell migration and invasion by targeting tumor‐suppresser gene SEPT7.38 MiR‐433 was reported to be commonly dysregulated in GBMs and suppressed glioma cell proliferation, migration, invasion, and enhanced sensitivity to TMZ therapy.39, 40 Regarding miR‐759 and miR‐1248, no biological or clinical evidences have been reported in cancers so far. Here, SEPTIN7 is linked to central nervous system cancer.