The pooled results in the present study were sensitivity of 0.69 (95%CI=0.62-0.76), specificity of 0.79 (95%CI=0.70-0.86), and the AUC of0.79 (95%CI=0.76-0.83), suggesting that H19 may be a potential biomarker to discriminate cancer patients from normal people. The gene discussed is H19; the disease is cancer.