In present meta-analysis, a pooled PLR of 3.31 (95%CI=2.29-4.78) and NLR 0.39 (95%CI =0.31-0.49) suggested that patients with cancer have a 3.31-fold higher possibility of being H19 positive for patients with cancer compared with controls, and 39% of all individuals have negative results, implying that the diagnostic value of H19 is relatively moderate. This evidence concerns the gene H19 and cancer.