During our exploration of the molecular mechanisms underlying mouse invasive bladder carcinogenesis, a marked conversion of microtubule associated protein 1 light chain 3 (LC3) from LC3‐I to LC3‐II, upregulation of autophagy‐related protein ATG7 was unexpectedly observed in mouse invasive BCs (n = 5) (Figure1A), revealing the potential association of autophagy with BC invasion. The gene discussed is MAP1LC3A; the disease is breast cancer.