ARHGDIA, ARHGDIB, RAC1,2,3, and ras homolog gene family, member A (RHOA) are key regulators of actin polymerization, cell migration, and cancer invasion.18 To clarify the mechanism underlying the ATG7 regulation of BC invasion, ARHGDIA, ARHGDIB, RAC1,2,3, and RHOA proteins were determined. Here, RAC1 is linked to breast cancer.