RHOA and cancer: ARHGDIA, ARHGDIB, RAC1,2,3, and ras homolog gene family, member A (RHOA) are key regulators of actin polymerization, cell migration, and cancer invasion.18 To clarify the mechanism underlying the ATG7 regulation of BC invasion, ARHGDIA, ARHGDIB, RAC1,2,3, and RHOA proteins were determined.