ERBB2 and breast cancer: The current recommendation regarding neoadjuvant therapy options for HER2-positive breast cancer in National Comprehensive Cancer Network (NCCN) guidelines contains many regimens, including combinational therapies: chemotherapy+trastuzumab+ pertuzumab (CTP), trastuzumab+emtansine+pertuzumab (MP), chemotherapy+ trastuzumab (CT), chemotherapy+pertuzumab (CP), trastuzumab+ pertuzumab (TP), chemotherapy+ trastuzumab+lapatinib (CTL), and chemotherapy plus lapatinib (CL) [14].