CXCR2 and neoplasm: Interestingly, CXCL5, a chemokine known for its role in promoting the recruitment of MDSCs and TAMs towards tumor sites24,25 and its receptor CXCR2 in addition to the Tregs transcription factor FOXP3 were among the highly differentially expressed between the XRT group and XRT + GLZ group (Fig. 3b).