Additionally, we found that Scn2a+/− and Scn2afl/+/Emx mice but not Scn2afl/+/Vgat mice showed SWDs during behavioral quiescence, although these were milder than those in Stxbp1+/− mice15, suggesting an overlapping pathological circuit for absence seizures in Stxbp1+/− and Scn2a+/− mice. This evidence concerns the gene STXBP1 and Generalized non-motor (absence) seizure.