A recent report that the SWI/SNF complex interacts with EWS-FLI1 and targets tumor-specific enhancers in Ewing sarcomas24, suggesting a broader relationship between SWI/SNF complexes with ETS family transcription factors; (2) ELK1, a target of the Ras/Raf/MAPK pathway, (3) ATF2 and CREB, related with the cAMP and apoptosis pathways, which have been shown to interact with SWI/SNF25. The gene discussed is SMARCA1; the disease is neoplasm.