CD8A and neoplasm: Immunofluorescence analysis performed 12 days after the first treatment with OxPt/DHA plus α-PD-L1 showed significant increase in the density of infiltrating CD3ε+ cells, which were primarily CD8+ (Fig. 8a, b, Supplementary Figure 35,36), providing the evidence for treatment-related change in the tumour microenvironment increasing the number of cytotoxic T cells.