SYP and neoplasm: Similarly to the SCLC-like tumors in the lungs of the Lmnb1+/− mice (Fig. 9, A–D), the cells in the tumor nodules in livers and kidneys were small with scant cytoplasm, expressed CGRP, Syp, and PanCK, but were negative for CD45 and were found close to blood vessels (Fig. S5 G), suggesting that these might be extrapulmonary metastases rather than primary tumors in these organs.