It is known as chloroma because of its greenish hue due to the presence of intracellular myeloperoxidase.It is most frequently associated with AML-M2, but has also been described in association with other myeloproliferative diseases, like chronic myeloid leukemia (CML), polycythemia vera, hypereosinophilia, and myeloid metaplasia [7]. The gene discussed is MPO; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.