The most frequently methylated genes in cervical cancer are cell adhesion molecule 1 (CADM1), Cyclin A1(CCNA1), cadherin 1 (CDH1), death-associated protein kinase 1 (DAPK1), Erythrocyte membrane protein band 4.1 like 3 (EPB41L3), myelin and lymphocyte (MAL), paired box 1 (PAX1), PR domain containing 14 (PRDM14,) and telomerase reverse transcriptase (hTERT) [64, 66–69]. The gene discussed is EPB41L3; the disease is cervical cancer.