CXCR4 and Familial prostate cancer: Supporting our data with ovarian, breast, glial, and prostate cancer cell lines, it was reported very recently that MF inhibited migration induced by progesterone in human astrocytoma cells [38], that both MF and its metabolite metapristone inhibited the chemotactic migration and mobility in SKOV-3 and IGROV-1 ovarian cancer cell lines facilitated by activation of the chemokine SDF-1/CXCR4 [29, 39], and that MF inhibited migration and invasion of endometrial carcinoma cells [40].