The top five KEGG pathways observed in these proteins were pathways in cancer (red; eight proteins, p = 5.44 × 10− 6), hepatitis B (purple; five proteins, p = 0.0002), pancreatic cancer (green; four proteins, p = 0.0002), prolactin signaling pathway (yellow; four proteins, p = 0.0002) and prostate cancer (lilac; four proteins, p = 0.0004). The gene discussed is PRL; the disease is cancer.