ALK and lung adenocarcinoma: KARPAS 299 is a T-cell lymphoma cell line carrying the NPM-ALK gene fusion [28]; KM-12 is a colorectal cancer cell line we had previously reported to express the chimeric TPM3-TRKA protein [29]; LC-2/ad is a lung adenocarcinoma cell line harboring a CCD6-RET fusion [30]; U-118 MG is a glioblastoma cell line characterized by the presence of a FIG(GOPC)-ROS1 rearrangement [31].