Besides changes in IgE-titer, the addition of OIT to scFOS/lcFOS diet also results in a beneficial decreases in probability of high earswelling (from 80.11% to 55.36), high mMCP-1 (66.72 to 32.46%) and a decrease in anaphylaxis-associated drop in body-temperature (from 33.54% to 20.63). This evidence concerns the gene IGHE and anaphylaxis.