Indeed, previous studies demonstrate that cTnT is associated with left ventricular hypertrophy26 and coronary plaque count, and plaque phenotype, as well.27,28 The MI and CHD outcomes were associated with cTnT in unadjusted models, and with cTnI in adjusted models, so the lack of association is not explained by outcome misspecification. This evidence concerns the gene TNNI3 and coronary artery disorder.