For instance, patients with neuromuscular diseases but with no evidence of heart disease may have elevated cTnT, but not an elevated cTnI.30–32 cTnT is also known to be a strong predictor of adverse noncardiac outcome following abdominal surgery.33 As such, different etiological causes of elevations in cTnI and cTnT, and consequently different downstream risks, may be sufficient to explain our findings. This evidence concerns the gene TNNI3 and neuromuscular disease.