The rate of tumor formation in vivo in CXCL14-expressing vector-transfected tumor cells (HSC-3-CXCL14) in athymic nude mice or T and B cell-deficient SCID mice was significantly lower than that of mock vector-transfected control cells, although the growth rates of the expression vector-transfected and mock vector-transfected cells were not different under in vitro culture conditions [7,9,10]. Here, CXCL14 is linked to neoplasm.