By measuring the concentration of superoxide dismutase (SOD) and glutathione peroxidase (GSH-PX) in the serum of rats, it was found that the SOD and GSH-PX levels in the T2DM group were significantly decreased when compared with the NC group (p < 0.05), while those in the Met and PAGR treatment groups were markedly increased when compared with the T2DM group, with significant differences between the Met and PAGR Hig groups (p < 0.05) (Figure 3c,d). The gene discussed is SOD1; the disease is type 2 diabetes mellitus.