Moreover, by subgrouping TRPML-1+ GBM patients according to ROC analysis (Figure 8d) in TRPML-1 > 1, TRPML-1 ≤ 1 the OS were of 28 and 17 months, respectively (p < 0.0298, HR = 2.2018, 95% CI 1.1221–9.4147) (Figure 8e). The gene discussed is MCOLN1; the disease is glioblastoma.