FOXO1 and cancer: We found a total of five shared transcripts (Cav1, Cxcl12, Foxo1, Mef2c, and Junb) (Figure 5B), and most importantly, these five transcripts revealed seven new microRNA-mRNA interactions in muscle wasting in cancer cachexia (miR-27a/Foxo1, miR-27a/Mef2c, miR-27b/Cxcl12, miR-27b/Mef2c, miR-140/Cxcl12, miR-199a/Cav1, and miR-199a/Junb) (Table 3).