In addition, we also identified 56 differentially expressed microRNAs, and further analyses found that five potential altered microRNA–mRNA interactions, including hsa-miR-939-5p–PLXNA4, hsa-miR-3918–CTIF, hsa-miR-4768-5p–PDE5A, hsa-miR-1273g-3p–VPS53, and hsa-miR-1972–PCSK9, might be important changes in response to EGCG treatment in IPF fibroblasts. Here, CTIF is linked to idiopathic pulmonary fibrosis.