INS and Hypoglycemia: In the repeated-hypoglycemia group (n = 4), BG levels 2 h after injection of insulin were significantly reduced from the matched preinjection time points (Fig. 1C): 3.1 ± 0.1 mM (day 1), 2.8 ± 0.2 mM (day 2), and 2.7 ± 0.1 mM (day 3).