LEP and infection: The Lep-vesicle-recycling endosomes in the cells co-localized with Sec15 or Sec3, with maximum co-localization percentages of 73.7–84.2% or 69.2–81.9% at 8–12 hr during infection with L. interrogans strain Lai (Figure 4A,B,D,E and Figure 4—figure supplement 1A-B ).