In particular, E‐cadherin, encoded by CDH1, was a candidate because it not only is the most prominent inducer of EMT in HCC39 but also is directly correlated with a poor prognosis and short survival rates for HCC patients.40, 41 Elevated TRERNA1 regulated the tumour metastasis‐related gene CDH1 expression, although the expression level of β‐catenin and vimentin was also changed in enforced or knocked‐down TRERNA1 cells, respectively. This evidence concerns the gene CDH1 and hepatocellular carcinoma.