TRERNA1 and neoplasm: We also noted that the loss of function of E‐cadherin often occurs in migratory cells and is related to tumour metastasis.23 In the present study, we found that elevated TRERNA1 decreased the expression level of CDH1 by Western blotting; conversely, the CDH1 expression level was restored after the knockdown of TRERNA1 (Figure 3C; Figure S4A,B).