CDH1 and non-small cell lung carcinoma: Additionally, NSCLC cells expressing a high level of six2 and a low level of E‐cadherin were followed by a high level of E‐cadherin promoter methylation, while normal lung epithelial BEAS‐2B cells expressing a low level of six2 and a high level of E‐cadherin had correspondingly a low level of E‐cadherin promoter methylation (Figure 5D).