Studies have demonstrated that Ox-LDL significantly induced lincRNA-DYNLRB2-2 expression, which promoted ABCA1-mediated cholesterol efflux and inhibited inflammation through G protein-coupled receptor 119 (GPR119) in acute monocytic leukemia (THP-1) macrophage derived foam cells [86]. The gene discussed is GPR119; the disease is acute monocytic leukemia.