MEF2C and amyotrophic lateral sclerosis: Previous studies by our research workgroup on transgenic SOD1G93A mice suggested five genes, Mef2c (myocyte enhancer factor 2C), Gsr (oxidative stress metabolism), Col19a1 (collagen, type XIX, alpha 1), Calm1 (calmodulin 1), and Snx10 (sorting nexin 10), as potential genetic biomarkers of longevity in transgenic SOD1G93A mice, one of the best-characterized animal models for ALS that resembles both clinical and pathological characteristics of ALS patients [9,10].