COL19A1 and amyotrophic lateral sclerosis: In contrast, COL19A1 levels were found significantly associated with sporadic ALS patients (OR: 16.106, CI: 2.294-113.053, P =0.005), with patients that share an age at onset lower than 55 years (OR: 2.543, CI: 1.007-6.422, P =0.048), and a defined El Escorial criteria (OR: 2.955, CI: 1.214-7.192, P =0.017), highlighting that COL19A1 levels could be more indicative of an earlier worsening in the functional state in the ALS patients.