Mice with heart failure and inducible cardiomyocyte-specific knockout of the sarcoplasmic reticulum Ca2+-ATPase (SERCA2KO) exhibited an increase in circulating levels of eotaxin, granulocyte-colony stimulating factor (G-CSF), monocyte chemoattractant protein-1 (MCP-1), and macrophage inflammatory protein-1beta (MIP-1β) [66]. Here, CCL11 is linked to heart failure.