CAND1 and atherosclerosis: By analyzing Pathway analysis results, we found that among the top 20 signal pathways with the most target gene enrichment, 13 pathways contain the target gene of miRNA-933, including: CCDC97, BDNF, CAND1, DMRTA2, MAP4K4, PRKACB, MID1IP1, SLC16A2, ADCY9, FCHSD2, LRPAP1, etc. Pharmacogenomics studies have shown that the ADCY9 genotype determines the effects of CETP (cholesteryl ester transfer protein) inhibitor dalcetrapib on cardiovascular events and atherosclerosis [25], although the specific mechanism is not clear.