TRPM6 and neoplasm: Interestingly, five genes were highly deregulated between the two tissues (Figure 1B): (i) KCNN4 and TRPM2 were upregulated in tumor tissues with a fold-change of 1.24 and 1.28 (Table S2), respectively; (ii) while KCNMA1, KCNMB1 and TRPM6 were significantly downregulated in tumor tissues by −1.66, −1.73 and −2.76 fold, respectively (Table S2).